It’s Difficult to Stop the Spread, But…

We can DRAMATICALLY reduce human susceptibility and minimize symptom severity!

How? Two very simple, effective and easy steps:

  1. Keep your nose, throat and lungs HYDRATED. The healthier your mucous membrane barrier is (the Glycans that acts as a fortress protecting your cells), the COVID-19 virus proteins will be carried out of your airways via your mucous rather than latching on to your cells and multiplying.
    1. If you are NOT well hydrated and the INDOOR air is DRY due to your HEAT being on in the fall and winter months, your Glycans get dehydrated and full of holes (akin to the dragon breathing fire at the fortress walls in Game of Thrones, breaking them down). If dehydrated, the virus proteins therefore can invade, latch on and multiply!

  2. Do NOT be deficient in your Vitamin D levels! The majority of patients that have died with active COVID-19, were DEFICIENT in VITAMIN D!
    1. The darker your skin, the more prone you are, inherently, to be Vitamin D deficient!

Are you wondering why MOST of the NFL players that have tested positive for COVID-19 show little to no symptoms and are rid of the virus within a few days? It is most likely DUE to the fact that they are healthy and keeping their internals well-hydrated and in turn, their symptoms are MINIMAL if ANY!

This is also why the majority of people that contracted the virus during the summer months had relatively minor and negligible symptoms, very low mortality rate; due to the HUMIDITY indoors and the summer sun offering the needed Vitamin D!

With the winter wave of COVID-19 beginning to hit the world (due to its inherent dryness in the air), this is a very good time to tell everyone you care about to simply hydrate and keep up with the proper Vitamin D levels!

A paper, led by Gordan Lauc, PhD, on humidity and COVID-19 severity is finishing review and should be published soon (preprint is here https://www.medrxiv.org/content/10.1101/2020.07.11.20147157v2)

Gordan Lauc, PhD; one of the leading researchers and voices of Glyconomics. If you have an interest in interviewing or speaking with Gordan, please let me know?

  • Professor of Biochemistry and Molecular Biology at the University of Zagreb
  • Director of the National Centre of Excellence in Personalised Healthcare
  • Honorary Professor of the University of Edinburgh Honorary Professor of the Kings College London
  • Member of the Johns Hopkins Society of Scholars Co-Director of the Human Glycome Project

Current Projects:

Business Consultant for AtmosAir

Our bi-polar ionization solution ensures Covid-19, as well as other pathogens and odors, are continuously neutralized and deactivated from your indoor air and exposed surfaces (tested and verified at 99.92% by Microchem Labs).

AtmosAir technology easily integrates into your existing HVAC system and ensures all airflow passes across its patented bipolar ionization tubes to energize the air with positive and negative ions throughout all of the spaces served by the HVAC duct system, effectively and continuously sanitizes contaminants as it encounters them.

One of Norm’s initial accomplishments with AtmosAir was to get their solutions to become an integral part of McDonald’s HVAC COVID-19 Global Guidance.


Business Consultant for On the Spot Ads:

Just when you thought that every inch and every piece of real estate has been exploited for advertising purposes, along comes On the Spot Ads, who has cleverly targeted the white line spaces of parking lots for a new form of ground-based location-relevant advertising.


Senior Advisor, Strategy & Alliances for Sports Engineering Inc.

Our purpose is to transform performance footwear by shaping, redistributing, and managing horizontal shear and rotational force.  Our patented technology limits the horizontal shear forces within the foundation of the shoe, to improve performance and protect the athlete. Chronic injury may result from overuse and fatigue resulting in poor or changing biomechanics. We believe a byproduct of our SmartSpring suite will help to reduce fatigue and allow consistent biomechanics, thereby mitigating ankle and knee injuries.


Business Consultant for SupraCam:

Supracam is a point to point, cable camera system that provides aerial camera shots for broadcast sports and entertainment events. The Supracam system consists of everything needed to set up aerial camera shots from small indoor events to stadiums and even between buildings in a downtown setting.

We are currently at the US Tennis Open doing the amazing aerial shots:
The long-run two-point system over the grounds again (a little longer and higher than last year) and our four-point system over the court inside Armstrong stadium.

SupraCam.tv

Fighting Viruses with Glycans

Original article appears on GlycanAge by Dr. Gordon Lauc, PhD
health · 8min

COVID-19 has developed into global pandemics, which we probably cannot stop any more. The virus is not very deadly but is spreading rapidly and can cause collapse of the healthcare system, even in developed countries like Italy. Therefore, we have to do our best to slow the spread of the virus, so that people that require hospital care get infected in a wider time window. This is the responsibility of each and every one of us.

In addition to avoiding social contacts and washing hands often, there is an additional essential protective measure that is frequently forgotten. Our mucosa (a membrane that lines inside of our mouth, nose, all airways, eyes, etc) is protecting our cells with a thick layer of glycans, but it has to be moist to be a functional barrier. Airconditioned spaces (both heated and cooled) generally have very low humidity, which dries out mucosal surfaces and makes them vulnerable to infection.

Since absolute humidity is strongly dependant on temperature, each time we open windows during the winter we lose 1-2 liters of water from an average room. This then dries our mucosal surfaces, which then become porous and do not protect us from viruses anymore. Fortunately, this can be fixed easily either using different humidifiers or by simple boiling of water. However, it is important to note that it is often needed to evaporate at least 3-4 liters of water per day to reach humidity levels of approx. 50% that is needed to keep our mucus flowing and protecting us from viruses and bacteria.

Viruses are our eternal “enemy” and we are fighting this war for millions of years. We lost a couple of battles, but we are still winning the “war” and will also survive this latest outbreak of the virus. Two main weapons in our arsenal for the “war against viruses” are (1) the immune system and (2) glycans. We are all aware of the importance of the immune system, so I will here present some evidence about the importance of glycans.

Our cells are protected with a thick layer of glycans (Photo adapted from Sun WW et al, Communication biology 3, 5; 2020)

As it is clearly shown in the photo above, our cells are covered with a thick layer of glycans (called glycocalyx). Any virus or bacteria that want to infect our cells has to first pass through this glycan shield. Most interactions between us and pathogens involve glycans and inter-individual variation in glycan diversity provides us with the ‘herd innate protection’ (Le Pendu et al, Current Opinion in Virology 88-94, 2014). Mucins secreted to our body fluids represent an important protective mechanism that attenuates viral infectivity (Wheeler et al, Nature Microbiology 4:2146–2154, 2019). However, for this barrier to be functional, it has to maintain a constant flow of mucins that mimic glycans on our cell surface and block infection. If exposed to dry air, these barriers dry out, cracks are forming, and viruses and bacteria have free access to our cells. Animal experiments showed that increasing relative humidity from 20% to 50% can decrease mortality by nearly 50%, indicating that the effect of low humidity is very strong. During the day this can be compensated by frequent drinking of water, but low humidity in places where we sleep can really dry out our mucosa and facilitate the spreading of both viruses and bacteria. This is the most probable cause for seasonal variation in respiratory infections, but also for frequent infections during long haul flights.

A close up of a flowerDescription automatically generated
Coronavirus spike Glycoprotein with its numerous glycans on the surface (adapted from Wheeler at al, BioRxiv, 2020)

Updated on March 21st, 2020

Recent data from China suggest that this is also true for COVID-19, since both higher temperatures and higher relative humidity significantly reduced transmission of the SARS- Cov-2 virus (Wang et al, SSRN, 2020)

Updated on March 24, 2020

An important review article just got published in Annual Reviews of Virology. This is not direct COVID-19 data, but many things can be extrapolated since it considers all respiratory viruses. Key figures from that review are copied below, together with the recommendations on how to limit virus transmission in winter.

The review also lists numerous research papers that demonstrated the efficiency of humidification of air on the reduction of transmission of respiratory viruses:

• Ritzel G. 1966. Sozialmedizinische Erhebungen zur Pathogenese und Prophylaxe von Erkältungskrankheiten. Int. J. Public Health 11:9–16

• 123. Sale CS. 1972. Humidification to reduce respiratory illnesses in nursery school children. South Med. J. 65:882–85

• Green GH. 1974. The effect of indoor relative humidity on absenteeism and colds in schools. ASHRAE Trans. 80:131–41

• Green GH. 1985. Indoor relative humidities in winter and the related absenteeism. ASHRAE Trans. 91:643–56

• Green GH.1982. The positive and negative effects of building humidification.ASHRAE Trans. 88:1049– 61

• Gelperin A. 1973. Humidification and upper respiratory infection incidence. Heating, Piping, Air Conditioning 45:77–78

• Shaman J, Kohn M. 2009. Absolute humidity modulates influenza survival, transmission, and seasonality. PNAS 106:3243–48

• Reiman JM, Das B, Sindberg GM, Urban MD, Hammerlund MEM, et al. 2018. Humidity as a nonpharmaceutical intervention for influenza A. PLOS ONE 13:e0204337

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Norm’s Suggestion of the Day; Get Humidifiers for your Bedrooms

The 25 Best Humidifiers of 2020 - Smart Style Today

I have been fortunate to work with a handful of incredible doctors and scientists who specialize in infectious disease, disease control as well as building A.I. “wellness monitoring” devices.  Their urgent recommendation is an easy step to take in the fight against the Coronavirus in your home (and PLEASE for the elderly in your family).  The important take away from this entire message is to achieve humidity above 50%, especially at night while you sleep to maintain hydration.

  1. By keeping our mucous membranes moist, we maintain a natural barrier to infection that’s like a “bulletproof vest” protecting our lungs, nose and mouth from infection. Dry air, especially while sleeping, makes us vulnerable to infection.  Viruses are 10-100X more viable in dry air.
  2. High humidity causes “friction” in the air that limits the distances that viruses can spread through the air. It markedly decreases the risk of person-to-person spread of infection.
  3. Moisture keeps virus particles on surfaces from drying out, going airborne and getting into our lungs.

In epidemiology, you have transmission and susceptibility.  Transmission is what sick people do and susceptibility is the measure of how difficult it is for well people to fend off illness.

Healthy lifestyles make for less susceptibility.  Respiratory diseases enter through the lungs.  Arguably sinuses but they’re fairly hardened.  We know this because 20% of humans have staph in their nasal passages and 20% of those are MRSA.  But the body is not infected.  So the lower respiratory tract is the area we want to protect.  Therefore the cilia, mucus coating the lungs (essentially skin) are able to stop the big droplets if they are properly hydrated. A doctor at Duke who obsessively studies cystic fibrosis (his son suffers) finds that around 65% or less hydration in the lung tissue makes you susceptible.  So if you breathe moist air (OR HYDRATE), you’ll avoid it.  At 15%RH room temperature you exhale about 20x more moisture than you inhale. At 50% its 5x.  So after 8 hours of not drinking water, you’re probably dehydrated when you wake up.  Getting on a scale at night and weighing yourself in the morning will prove this to you.

————-
 
From Stephanie Taylor, MD, M. Arch, CIC (The Power of Indoor Air)
Graduated with Honors from Harvard Medical School, Boston, Mass.
 
This virus attaches really deeply to the receptors in your lungs. So, while the common cold more likely attaches to your sinuses and throat, this attaches deep in your lungs, which causes you to get sicker.
 

It’s very clear that it’s transmitted through the environment. And this is both alarming and good news. We’ve known for a long time that viruses can be spread through droplets. If somebody sneezes and one of those wet droplets lands on you, or a few feet away from you, and then you rub your nose or the virus or bacteria get into your body, you have a high chance of getting sick. But the transmission pathway that we haven’t really wanted to think about is when an infected person sneezes, coughs, or simply breathes droplets into the air. If the air is dry, those droplets shrink and desiccate to reach a moisture equilibrium within the air around you. And we now know that the viruses in those very tiny desiccated particles can go up in the air, they can travel into an HVAC system and re-infect people who are quite far away and have had no immediate contact. That’s one of the things that makes this virus alarming. We can no longer deny airborne transmission of infectious aerosols.

The concept of airborne transmission of infectious droplets is scary, but we can help control it by keeping the relative humidity in our breathing zone or in our buildings between 40%-60%. This has turned out to be the magic zone. I think Mother Nature gave us that opportunity so we could survive. If you’re outdoors, even say in the winter, your relative humidity is typically in a fairly safe zone. It’s cold out and the low moisture content puts the relative humidity at 50%-60%. When we bring that cold air in the building, we warm it up to comfort temperatures, and all of a sudden relative humidity falls to 20%. And this is where we’re getting into trouble. Data and research show us that if people in offices, hospitals, and schools manage their indoor relative humidity at 40%-60%, humans’ mechanisms for physiological defense are improved.

There is some brilliant research from Yale that came out last May that really helps us understand how appropriate water vapor in our breathing zone bolsters our immune system.  If you can humidify your indoor environment to this moderate zone, you actually bring out the infectious particles. They are brought down from the air. Research from 2010 as well as up to up to a week ago from the NIH [National Institute of Health], Princeton, and Harvard shows that viruses in the air and on surfaces are inactivated when the relative humidity is maintained in that zone.

As human beings, we don’t do well in dry air, and these quickly mutating viruses and bacteria do. In dry air, they’re like, great, we can mutate, we can fly around, and we can find new hosts. So, one thing we can do is really think about the air. We can humidify from 40%-60%. There are other strategies, like UV-C light, which de-activates many organisms. Filtration can be very beneficial. Hydrogen peroxide misting is another one, and I’m sure I’m missing some. The one I like best is humidifying the indoor environment, because not only does it help support the air we breathe, it also bolsters our own immune systems, which is critical, especially now.

  • Jeffrey Gusky, MD is an emergency medicine physician in Dallas, Texas / Emergency Response Doctor in COVID-19
  • Stephanie Taylor, M.D., M. Arch, CIC
  • Rik Heller, Chairman, and CEO of Wello – Pioneering inventor of automated wireless temperature monitoring sensors and cloud-based technology for healthcare and food services; he recognized the need for improved disease control and contagion management.
  • Prof Gordan Lauc, PhD: Director of the National Centre of Research Excellence in PHC; Director of the Human Glycome Project / Member of the Johns Hopkins Society of Scholars
    • Fighting Viruses with Glycans: Our mucosa (a membrane that lines inside of our mouth, nose, all airways, eyes, etc) is protecting our cells with a thick layer of glycans, but it has to be moist to be a functional barrier.
————–

Please stay hydrated, healthy and safe!
All the best
Norm

 

“Hey Norm, This is doubtful!  Humidity in Miami is regularly over 75% and the virus seems to be spreading there just fine”

Rik Heller’s response:

Humidity is friction to epidemics. The problem with Florida is that AC is a dehumidifier. You can see the water coming out of the AC when it’s on. The AC is sized for comfort and lowers the humidity indoors to ~40%. Covid19 is very infectious as much as Norovirus (the Chipotle virus). The reason it travels around Cruise ships is because the AC desiccates air by 20% indoor @ room temp.

Anything around salt water gets a constant absolute humidity. It’s hard to talk RH, only AH or dewpoint. AH is grams/m3 .  Much simpler than RH to use. Rh is very misleading and hard for anyone to think about except at constant temperatures like to room temperature.

It’s why this subject is so confusing. Adding metric over initial measurements increases the confusion.

Norm Joins Artificial Intelligence Company Founded by A.I. Pioneer Who Coined The Term ‘Artificial General Intelligence’ (AGI)

As the world’s foremost authority on conversational A.I. based on a cognitive architecture, or what DARPA calls ‘The Third Wave of AI’, Peter Voss has been working with his team of A.I. Psychologists for more than 15 years to develop, commercialize, and perfect this technology.

The first generation of Aigo technology has been successfully commercialized for more than 10 years through SmartAction, while the second generation is now being aggressively commercialized via Aigo.AI.

Norm joins Aigo.AI as a Business and Sales Consultant, introducing an adaptive, contextual, conversational Artificial Intelligence based on cognitive architecture.  It remembers what is said, and it constantly learns; it’s so much more intuitive and intelligent than current chatbots (ML/DL), virtual assistants, Siri, Alexa, etc.

  • Aigo is the most advanced Natural Language Interaction platform.
  • Aigo is a generic intelligence engine – it is domain agnostic.
  • Aigo is software – it is hardware agnostic.
  • Aigo is multi-modal – Talk, Text, or Touch.
  • Aigo increases stickiness, loyalty, and user adoption by creating engaging customer experiences.
  • Aigo’s Brain scales from 10 users to 100 million users

Aigo is built on a mind-like integrated cognitive architecture. This is radically different from the other current chatbots and so-called ‘personal assistants’ and puts Aigo ‘Light Years’ ahead.

Aigo’s human-like cognition allows it to:

  • Remember what was said and utilize this in future conversations
  • Understand context and complex sentences
  • Use Reasoning to disambiguate and answer questions
  • Learn new facts and skills interactively, in real-time
  • Have ongoing, meaningful conversations
  • Hyper-personalize experiences based on user’s history, preferences and goals

 

Norm Joins Centurion VR as Strategic Advisor

Centurion VR is transforming the sport of cricket with its patented VR technology. Star India, the world’s leading broadcaster of cricket and a subsidiary of The Walt Disney Company, is a major shareholder in Centurion VR.

Centurion’s ground-breaking virtual reality experience allows you to face bowling from some of the best cricketers in the world giving you the opportunity to hit them for a six or see if you will have your stumps rearranged. The system means users will be facing a virtual version of super quick yorkers and bouncers, or see the ball flying past their outside edge.

Centurion’s product has already proved to be a huge hit internationally, and with Centurion heading to the CPL this year, it means fans across the Caribbean can be closer to the action than ever before with the chance to enjoy the world’s best cricket batting simulation during this year’s tournament.

Norm Joins Supracam as Special Business/Sales Advisor

Supracam is comprised of a unique “cable camera” service, engineering and tech group that specializes in amazing live video shots for sporting events, music concerts and festivals from cables above:

Recent Projects include:

  • CBS Thursday Night Football
  • CBS Super Bowl 50 (Emmy Award)
  • NBC The Players Championship
  • NBC The US Open
  • ESPN NBA Draft
  • MBLAM Arizona Bowl
  • NBC Phoenix Open
  • NBC Ryder Cup
  • NFLN and ESPN NFL Draft
  • NFLN Super Bowl 50 Opening Night
  • NFLN Super Bowl LII (Emmy Award)
  • Taylor Swift – Red Music Video
  • Steve Miller Band Concert

Supracam’s technologies were used by James Cameron in the original Avatar (the movie) and are currently being deployed by the latest Avatar production team in New Zealand.

Norm sets up vGolf Demonstration with Justin Timberlake

Norm finds golf tech start-up vGolf the perfect match made in golf heaven and coordinates a demonstration for Justin Timberlake.

Justin puts on the Augmented Reality glasses and plays a fairway at Troon North Golf Club, using a real golf ball, showing off his flawless swing using his favorite driver, all performed in a hotel conference room.

Image copyright Golf Digest

If interested to learn more about vGolf, please email or call me.

 

One of the Most Needed Technologies of our Time, Sadly; Sensor Device that Detects Gun Powder, Ammunition, Explosives.

Norm assists team that has developed the first portable sensor device to detect gunpowder across distances and barriers. Our patented technology accurately detects the gunpowder that is found in the ammunition of modern handguns, shotguns, and rifles.

We are working tirelessly to convert our technology into a digitized notification workflow that will be easy and cost-effective to use in wearable devices, entry-ways as well as allow it to be integrated into existing security systems.

We have technology that we believe will dramatically enhance public safety at movie theaters, live music and sporting events, schools, hotels, restaurants, malls, office buildings, apartment buildings, homes, etc.
If interested in more information, please email me

Norm Joins VR/AR Adtech Startup Admix as Business Advisor

Admix empowers VR/AR developers to monetize their content through interactive, programmatic brand placements. It the first and only programmatic route to buy VR/AR media, from premium advertising platforms like Verizon Media.

Over the past 18 months Admix has seen exponential growth thanks to a partnership with Oath (the parent company of Yahoo and AOL), launching a beta earlier this year which has seen over 100 VR/AR creators working with its platform.